Nano Therapeutics Research Laboratory

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Nanomedicine       Different nanoparticles made in the lab

Research

Immune System Boosted Combination Therapy | Cardiovascular Imaging and Therapy | Organelle-Targeted Delivery | Nanotheranostics | Affiliations | Research Support | Research Collaborators

Our research interests lie at the interface of chemistry and biology with particular emphasis on nanocarrier mediated intracellular delivery of payloads for potential applications in various diseases. The field of organelle specific targeted delivery of payloads has been mushrooming. Our research is directed to develop organelle targeted nanoparticles and to study nanoparticle assisted targeted delivery for possible applications in cancer, cardiovascular and neurodegenerative diseases. Our lab develops technologies that use a combination of conventional methods of cancer treatment and immunotherapy in a single nanoparticle platform.

We work in the areas of diagnosis and combination therapies for cancer and cardiovascular disease. Our research program includes design, synthesis, in vitro, and pre-clinical testing of different nanomedicine platforms. As a research team with a strong background in chemistry, we aim to provide the scientific community with valuable knowledge that can guide into the discovery of potential drug candidates and vaccines.

Currently we are working in the following research areas:

Project 1: Our research is directed to develop organelle targeted engineered nanoparticles that will offer several advantages over the existing drugs

Project 2: Our lab develops technologies that use a combination of conventional cancer treatment and immunotherapy in a single nanoparticle platform to provide powerful tool to treat metastatic cancer.

Project 3: We are working on combination of neuro-protectant stem cell therapy of stroke.

Project 4: We are involved in developing image-guided therapeutic nanoparticles for atherosclerosis.

Subgroups:

Immune System Boosted Combination Therapy

Cardiovascular Imaging and Therapy

Organelle-Targeted Delivery

Nanotheranostics

Research facilities at NanoTherapeutics Research Laboratory

Other UGA Affilations:

Shanta is part of various centers/initiatives at UGA

Research Support

We are grateful to various funding agencies and UGA for current and past support to do this exciting science. If you are interested in more information about supporting our efforts through philanthropy, research partnerships, please contact Dr. Shanta Dhar at shanta(at)uga.edu.

Current support:

Our research is currently supported by
  • American Heart Association National Scientist Development Award (14SDG18690009)
  • National Institutes of Health R56 (NIH High priority award) grant from the NHLBI (R56HL121392)
  • National Institutes of Health R01 award from NINDS (R01NS093314) for stroke therapy using targeted nanoparticles.

Past support:

Research Collaborators

  • W. Robert Taylor -- Emory link
  • Donald Harn -- UGA link
  • Raj Govindarajan -- UGA link
  • Franklin D. West -- UGA link
  • Simon R. Platt -- UGA link
Dept Back UGA

last modified 22nd March 2016