Nano Therapeutics Research Laboratory

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Publications

In Press |2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | Books/Chapters | Patents |

Citations > 1619 and h-index = 20

(33) Marrache, S. Pathak, R. K.; Darley, K. L.; Zaver, D.; Choi, J. H.; Kolishetti, N. K. and Dhar, S. "Nanocarriers as therapeutic platforms for tracking and treating diseases"
Curr. Med. Chem., 2013, In Press. Link

(32) Marrache, S. and Dhar, S. "Biodegradable synthetic high-density lipoprotein nanoparticles for atherosclerosis"
Proc. Natl. Acad. Sci. USA, 2013, 110, 9445-9450. Link

(31) Marrache, S.; Choi, J. H.; Tundup, S.; Harn, D. A. and Dhar, S. "Immune stimulating photoactive hybrid nanoparticles for metastatic breast cancer"
Integr. Biol. 2013, 5, 215-223. Link

(30) Marrache, S. and Dhar, S. "Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics"
Proc. Natl. Acad. Sci. USA, 2012, 109, 16288-16293. Link

(29) Dhar, S.; Kolishetti, N.; Lippard, S. J. and Farokhzad, O. C. "Targeted delivery of cisplatin prodrug for safer and more effective prostate cancer therapy in vivo"
Proc. Natl. Acad. Sci. USA, 2011, 108, 1850-1855. Link

(28) Roy, M.; Dhar, S.; Maitya, B. and Chakravarty, A. R. "Dicopper(II) complexes showing DNA hydrolase activity and monomeric adduct formation with bis(4-nitrophenyl)phosphate"
Inorg. Chim. Acta. 2011, 375, 173-180. Link

(27) Kolishetti, N.; Dhar, S.; Valencia, P.; Lin, L.; Karnik. R.; Lippard, S. J.; Langer, R. and Farokhzad, O. C. "Engineering of self-assembled nanoparticle platform for precisely-controlled combination drug therapy"
Proc. Natl. Acad. Sci. USA, 2010, 107, 17939-17944. Link

(26) Lee, T.; Zhang, X.; Dhar, S.; Faas, M. S.; Lippard, S. J. and Jasanoff, A. P. "In vivo imaging with a cell-permeable porphyrin-based MRI contrast agent"
Chemistry and Biology, 2010, 17, 665-673. Link

(25) Dhar, S.; Daniel, W. L.; Giljohann, D. A.; Mirkin, C. A. and Lippard, S.J. "Polyvalent oligo-modified gold nanoparticles as delivery vehicles for platinum(IV) warhead"
J. Am. Chem. Soc. 2009, 131, 14652-14653. Link

(24) Dhar, S. and Lippard, S. J. "Mitaplatin, A Potent Fusion of Cisplatin and the Orphan Drug Dichloroacetate"
Proc. Natl. Acad. Sci. USA, 2009, 106, 22199-22204. Link

(23) Dhar, S.; Gu, F. X.; Langer, R.; Farokhzad, O. C. and Lippard, S. J. "Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles"
Proc. Natl. Acad. Sci. USA, 2008, 105, 17356-17361. Link

(22) Tennyson, A. G.; Dhar, S. and Lippard, S. J. "Syntheses of {Ni(NO)}10 and {Co(NO)2}10 complexes supported by thiolate ligands: Insight into the nitric oxide chemistry of iron thiolate complexes in biology"
J. Am. Chem. Soc. 2008, 130, 15087-15098. Link

(21) Dhar, S.; Liu, Z.; Thomale, J.; Dai, H. and Lippard, S. J. "Targeted single walled carbon nanotube mediated Pt(IV) prodrug delivery using folate as homing device"
J. Am. Chem. Soc. 2008, 130, 11467-11476. Link

(20) Roy, S.; Patra, A. K.; Dhar, S. and Chakravarty, A. R. "Photosensitizer in a molecular bowl and its effect on the DNA binding and cleavage activity of 3d-metal scorpionates"
Inorg. Chem. 2008, 47, 5625-5633. Link

(19) Dhar, S.; Kodama, T. and Greenberg, M. M. "Selective detection and quantification of oxidized abasic lesions in DNA"
J. Am. Chem. Soc. 2007, 129, 8702-8703. Link

(18) Dhar, S.; Nethaji, M. and Chakravarty, A. R. "DNA cleavage on photoexposure at the d-d band in ternary copper(II) complexes using red-light laser"
Inorg. Chem. 2006, 45, 11043-11050. Link

(17) Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Steric protection of photosensitizer in a N,N-bis[2-(2-pyridyl)ethyl]-2-phenylethylamine-copper(II) bowl that enhances red light-induced DNA cleavage activity"
Inorg. Chem. 2005, 44, 8876-8883. Link

(16) Dhar, S. and Chakravarty, A. R. "Photosensitizer in a molecular bowl: Steric protection enhancing the photonuclease activity of copper(II) scorpionates"
Inorg. Chem. 2005, 44, 2582-2584. Link

(15) Patra, A. K.; Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Metal-assisted red light-induced DNA cleavage by ternary L-methionine copper(II) complexes of planar heterocyclic bases"
Dalton Trans. 2005, 896-902. Link

(14) Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Synthesis, crystal structure and photo-induced DNA cleavage activity of ternary copper(II) complexes of NSO-donor Schiff bases and NN-donor heterocyclic ligands"
Inorg. Chim. Acta. 2005, 358, 2437-2444. Link

(13) Gupta, T.; Patra, A. K.; Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Effect of copper-sulfur bond on the DNA photocleavage activity of 2-(methylthio) ethylpyridine-2-carbaldimine copper(II) complexes"
J. Chem. Sci. 2005, 117, 123-132. Link

(12) Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Effect of charge transfer bands on the photo-induced DNA cleavage activity of [1-(2-thiazolylazo)-2-naphtholato]copper(II) complexes"
J. Inorg. Biochem. 2005, 99, 805-812. Link

(11) Mukherjee, A.; Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Ternary iron(II) complex with an emissive imidazopyridine arm from Schiff base cyclizations and its oxidative DNA cleavage activity"
Dalton Trans. 2005, 349-353. Link

(10) Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Designing molecules for PDT: red light-induced DNA cleavage on disulfide bond activation in a dicopper(II) complex"
Dalton Trans. 2005, 344-348. Link

(9) Pradhan, R.; Thomas, A. M; Mukherjee, A; Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Synthesis, crystal structute and DNA hydrolysis activity of ternary (N-salicylidene-L-methioninato)copper(II) complexes of heterocyclic bases"
Indian J. Chem. 2004, 43A, 2307-2314. Link

(8) Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Synthetic analogue approach for the functional domains of copper(II)-bleomycins and its DNA cleavage activity"
Dalton Trans. 2004, 4180-4184. Link

(7) Gupta, T.; Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Bis(dipyridophenazine)copper(II) complex as major groove directing synthetic hydrolase"
Dalton Trans. 2004, 1896-1900. Link

(6) Dhar, S.; Reddy, P. A. N. and Chakravarty, A. R. "Intramolecular nucleophilic activation promoting efficient hydrolytic cleavage of DNA by (aqua)bis(dipyrido-quinoxaline)copper(II) complex"
Dalton Trans. 2004, 697-698. Link

(5) Patra, A. K.; Dhar, S.; Nethaji, M. and Chakravarty, A. R. "Visible light-induced nuclease activity of a ternary mono-phenanthroline copper(II) complex containing L-methionine as a photosensitizer"
Chem. Commun. 2003, 1562-1563. Link

(4) Dhar, S.; Senapati, D.; Reddy, P. A. N.; Das, P. K. and Chakravarty, A. R. "Metal-assisted red light-induced efficient DNA cleavage by dipyridoquinoxaline- copper(II) complex"
Chem. Commun. 2003, 2452-2453. Link

(3) Dhar, S. and Chakravarty, A. R. "Efficient visible light-induced nuclease activity of a ternary mono-phenanthroline copper(II) complex containing 2-(methylthio)ethylsalicylaldimine"
Inorg. Chem. 2003, 42, 2483-2485. Link

(2) Dhar, S.; Senapati, D.; Das, P. K.; Chattopadhyay, P.; Nethaji, M. and Chakravarty, A. R. "Ternary copper complexes for photo-cleavage of DNA by red light: direct evidence for sulfur to copper charge transfer and d-d band involvement"
J. Am. Chem. Soc. 2003, 125, 12118-12124. Link

(1) Dhar, S.; Reddy, P. A. N.; Saha, M. K.; Nethaji, M.; Mahadevan, S. and Chakravarty, A. R. "Effect of steric encumbrance of tris(3-phenylpyrazolyl)borate on the structure and properties of ternary copper(II) complexes having N,N-donor heterocyclic bases"
Inorg. Chem. 2002, 41, 3469-3476. Link

Book Chapters

(2) Dhar, S. and Lippard, S. J. "Current status and mechanism of action of platinum-based anticancer drugs", E. Alessio Ed.
Bioinorganic Medicinal Chemistry; Wiley-VCH, Weinheim, Germany, 2011, pp 79-95. Link

(1) Dhar, S. and Lippard, S. J. "Structural and mechanistic studies of anticancer platinum drugs: Uptake, activation, and the cellular response to DNA binding", A Bonetti et al. Eds. In
Platinum and other heavy metal compounds in cancer chemotherapy; Humana Press, NJ, 2009, pp 135-147. Link

Patents

(7) Dhar, S. and Marrache, S. "Nanoparticles for mitochondrial trafficking of agents",
Technology disclosure filed Link

(6) Dhar, S. and Marrache, S. "Apoptosis-targeting nanoparticles",
PCT Int. Appl. (2013), WO 2013033513 A1 20130307. Link

(5) Dhar, S.; Choi, J. H. and Marrache, S. "Immune-stimulating photoactive hybrid nanoparticles",
PCT Int. Appl. (2013), WO 2013012628 A2 20130124. Link

(4) Farokhzad, O. C.; Kolishetti, N.; Dhar, S.; Lippard, S. J. and Langer, R. "Particles for multiple agent delivery",
PCT Int. Appl. (2011), WO 2011084620 A2 20110714 Link

(3) Mirkin, C. A.; Giljohann, D. A.; Daniel, W. L.; Lippard, S.J and Dhar, S. "Polyvalent polynucleotide nanoparticle conjugates as delivery vehicles for a chemotherapeutic agent",
PCT Int. Appl. (2011), WO 2011028847 A1 20110310. Link

(2) Lippard, S. J.; Dhar, S.; Farokhzad, O. C.; Kolishetti, N.; and Gu, F. X. "Nanostructures for drug delivery",
PCT Int. Appl. (2010), WO 2010047765 A2 20100429. Link

(1) Lippard, S. J. and Dhar, S. "Platinum (IV) complexes for use in dual mode pharmaceutical therapy",
PCT Int. Appl. (2010), WO 2010027428 A1 20100311. Link

Dept Back UGA

last modified 15th June 2013